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The 7 Best Isekai Series with 50+ Episodes Currently Streaming

May 25, 2025 - Movies

The isekai genre has blown up over the past few years, and it’s quickly becoming one of the most popular in anime. There are a ton of great, new isekai series that have taken center stage, but few have run for more than 50 episodes. It’s exciting that there are so many great options out there, but out of them all, there aren’t many that a fan can sink their teeth into for more than a season or two.

Luckily, there are a few amazing, top-tier isekai series with more than 50 episodes. These series have multiple seasons, long, winding stories, and casts with backstories just waiting to be uncovered. There are also a ton of great isekai series readily available on the most popular streaming services. Fans don’t have to subscribe to an obscure website or sail the seas to check out great isekai anymore, as the best are on sites like Crunchyroll, Hulu, or other major platforms.

7

The Rising of the Shield Hero

Animated By Kinema Citrus and DR Movie, Based on the Light Novel Series By Aneko Yusagi

The Rising of the Shield Hero is one of the most divisive isekai series around. The series stars Naofumi Iwatani as the titular Shield Hero. He and three other Japanese men are summoned to another world with the task of defending it as the world’s heroes. Naofumi is the only hero to receive a defensive item as equipment, and he’s the only one of the four to not receive powerful magic as well.

From the beginning, The Rising of the Shield Hero sets itself apart from other isekai series. It’s a controversial series about redeeming oneself, finding people who see the most authentic version of a person, and working for a goal greater than revenge. Naofumi doesn’t get sucked into hatred like most others would in his position, making him an interesting isekai protagonist from the start. There are already 50 episodes across three seasons, and with the announcement of the fourth season, another dozen or more will be added.

6

Sword Art Online

Animated By A-1 Pictures, Based on the Light Novel Written By Reki Kawahara and abec

Sword Art Online isn’t just one of the best isekai series with more than 50 episodes, it’s a foundation of the isekai genre. It’s one of the best series animated by A-1 Productions, one of the best animation studios in Japan. Protagonist Kazuto “Kirito” Kirigaya has gone down in anime history as one of the most well-known main characters around. Sword Art Online is one of the most popular anime series on MyAnimeList.com as well, beating series like Naruto, Hunter x Hunter, and My Hero Academia.

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Sword Art Online takes place in the eponymous fictional video game of Sword Art Online (SAO). Once the game reaches 10,000 players, the creator of the game traps them within it, telling the players they aren’t allowed to leave until they conquer all 100 floors of Aincrad. It’s a compelling, intriguing story set within an interesting world filled with mystery. It also has way more than 50 episodes, giving anyone looking for a great series plenty to watch.

5

Inuyasha

Animated By Sunrise, Based On The Manga By Rumiko Takahashi

Inuyasha is a classic of the isekai genre. Inuyasha deserves a lot of credit for being a popular isekai series before isekai was a popular genre. Without this series, most of the best current isekai series around wouldn’t exist. Inuyasha introduced the West to the titular Inuyasha and Kagome Higurashi, two characters in pursuit of the sacred Shikon Jewel. The series takes place in the Edo period of Japan, giving it a historical edge that ages well.

Inuyasha is a fairly dark, serious series that tackles heavy topics with tact and grace. A lot of modern-day isekai series are fun, light-hearted, and filled with jokes. Inuyasha stands out because its tends to head in the opposite direction in terms of tone, providing audiences with over 150 episodes of gritty anime that set the stage for every isekai series that came after.

4

Mushoku Tensei: Jobless Reincarnation

Animated By Studio Bind, Based on the Light Novel Series By Rifujin na Magonote & Shirotaka

Mushoku Tensei: Jobless Reincarnation is one of the most controversial series of all time. While there are a ton of issues with the series on and off-screen, there’s no dying the enormous quality that Mushoku Tensei puts forward. The series is one of the most thorough, following Rudeus Greyrat from his previous life, to his reincarnation into a world of magic and monsters, to his eventual death as an old man.

There aren’t many series that follow their main character from their birth all the way to their death, leaving no stone unturned. Mushoku Tensei isn’t just thorough in its story: it has some of the best animation in isekai. Every inch of Mushoku Tensei looks like a visual masterpiece, with the smallest details brought to the highest quality. When Rudeus casts a fireball spell in a tundra, even the snow around him melts. It currently has just under 50 episodes, but with the third season coming up, that will change soon.

3

That Time I Got Reincarnated as a Slime

Animated By Eight Bit, Based on the Light Novel By Fuse and Mitz Vah

That Time I Got Reincarnated as a Slime is a romp of isekai series diverse in the topics it tackles. It follows Rimuru Tempest as he’s reincarnated into another world as a slime. While slimes are usually the weakest creatures in the worlds they inhabit, Rimuru is anything but, and he quickly becomes one of the strongest characters in That Time I Got Reincarnated as a Slime. The series is one of the best iskeais around because of how well it handles different tones.

That Time I Got Reincarnated as a Slime can be funny, serious, and action-packed. Each tone brings a lot to the series and makes it an interesting watch from start to finish. Rimuru is a busy character in his series as well. He starts That Time I Got Reincarnated as a Slime trying to figure out the world around him. Eventually, he decides to build his own kingdom, ascend to the rank of Demon Lord, and create a peaceful union between humans and monsters alike.

2

Overlord

Animated By Madhouse, Based on the Light Novel By Kugane Maruyama & so-bin

Overlord is one of the best isekai series ever made because of its premise and its execution. Most isekai series send their protagonist to another world and force them into the hero role. These characters are given amazing powers, a lot of responsibilities, and no freedom. Overlord does the exact opposite, giving its main character Ainz Ooal Gown plenty of power to wield however he wants.

Ainz is the titular Overlord. He rules his world how he sees fit, and it’s a lot different from any other protagonist in isekai. He dominates his enemies through fear and force, and it makes Overlord a refreshing isekai series. There aren’t many moments as uniquely brutal as watching Ainz destroy over 100,000 enemy soldiers in an instant, showing off so much power that even the soldiers fighting with him cower in fear.

1

Re:Zero – Starting Life in Another World

Animated By White Fox, Based on the Light Novel Series By Tappei Nagatsuki & Shin’ichirō Ōtsuka

Re:Zero – Starting Life in Another World is one of the darkest anime series ever. It’s easily the darkest isekai series and a show that stands out in the field of lighthearted, humorous competitors. The anime puts a spotlight on Natsuki Subaru, a shut-in reincarnated to a new world and given one of the most bitter-sweet powers in anime. He has the powerful Return by Death ability, giving him the opportunity to come back to life a few hours, or days, before he dies.

It’s a power that gives Subaru a unique opportunity to rewrite history, but it comes at a brutal cost. He constantly dies in gruesome ways, but due to his overwhelming determination to make things right, he always finds a way to persevere. Re:Zero has an incredible story, a huge world waiting to be explored, and some of the most adorable (and dangerous) side characters in anime.

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